Due to results from laboratory evaluation, the US FDA has learned that Zantac® and other ranitidine medications have a nitrosamine issue called N–nitrosodimethylamine (NDMA) at lower concentrations. NDMA is known as a likely human carcinogen – a substance may cause cancer in humans. NDMA is a classified environmental contaminant and observed in water and foods, including meat, dairy products, and produce.
What is NDMA?
N–nitrosodimethylamine (NDMA) is considered as a probable human carcinogen that means that it’s more probable than not to cause cancer in humans. NDMA has been studied in animal populations and found to increase the creation of cancer in the animals. The studies have increased the opportunity of an connection between NDMA and liver toxicity which may lead to the development of liver cancer and various connected conditions created from an NDMA–induced treatment of the liver.
The amount and duration of human NDMA exposure that can lead to the development of cancer is not precisely known. Also, the amount and length of the NDMA contamination of Zantac® and various ranitidine medicines are not precisely known. zantac
Connected with Exposure to NDMA
NDMA has been researched in animal populations and observed to increase the happening of cancer in the animals. Based on these studies, the US EPA classifies NDMA as a probable human carcinogen. The studies have increased the likeliness of an association between NDMA and liver toxicity that can lead to the creation of liver cancer and other related issues created by an NDMA injury to the liver. Others have claimed that NDMA may also be linked to other cancers such as:
Bladder Cancer, Colorectal Cancer, Kidney Cancer, Non–Hodgkin’s Lymphoma.
Has Other Ranitidine Products Also Been Affected?
Yes. The U.S. Food and Drug Administration has contacted health care professionals and consumers to three existing voluntary recalls of ranitidine.
Perrigo Company plc has voluntarily recalled over–the–counter (OTC) ranitidine tablets due to the possibility of N–Nitrosodimethylamine (NDMA) in the medicine.
Novitium Pharma LLC has voluntarily recalled all unexpired quantities and lots of ranitidine hydrochloride medication due to the possibility of NDMA in the medicine.
Lannett Company, Inc. has voluntarily recalled all unexpired lots of prescription ranitidine syrup due to the presence of NDMA found in the drug.
Should I Cease Taking Zantac® or Other Ranitidine Medicines?
On October 28, 2019, the FDA advised patients and consumers taking Zantac® and other ranitidine medications as follows:
“Patients taking prescription ranitidine who wish to stop should talk to their health care professional about other treatment options. Consumers taking OTC ranitidine, which is used to prevent and relieve heartburn associated with acid indigestion and sour stomach, may consider using other OTC products approved for their condition. FDA’s testing of samples of alternatives such as Pepcid (famotidine), Tagamet (cimetidine), Nexium (esomeprazole), Prevacid (lansoprazole), and Prilosec (omeprazole) show no NDMA in these medicines.”
Meneo Law Group is a leading consumer advocate for the recovery of damages due to NDMA injury. Feel free to contact us at any time to explore your injury and potential for recovery.